The emergence of two new villains threatens the city. First is , an electrical engineer who gains electric powers after an accident and becomes obsessed with destroying Spider-Man. Second is the Green Goblin (Dane DeHaan) , Peter's childhood friend Harry Osborn, who descends into madness. Simultaneously, Peter uncovers secrets about his father's past that could change everything he knows about his origins.

: Max Dillon, an overlooked electrical engineer at Oscorp, transforms into the powerful villain Electro after a freak accident involving genetically engineered eels.