Mitochondrial DNA (mtDNA), lacking robust repair mechanisms, mutates 10–100 times faster than nuclear DNA. v1.0 introduces a "parity matrix": each mitochondrion receives a synthetic, nucleus-encoded backup of all 37 mtDNA genes, translated locally via engineered RNA importers. When oxidative damage corrupts a native mtDNA copy, the parity matrix seamlessly replaces the faulty transcript within 0.3 seconds. This eliminates the heteroplasmy that drives metabolic aging, neurodegeneration (Leigh syndrome, Parkinson’s), and sarcopenia.